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Cystic fibrosis and pregnancy

^1. Wansbeck General Hospital, Woodhorn Lane, Ashington, Northumberland NE63 9JJ, UK Email: juliegoddard30{at}hotmail.com (corresponding author)
^2. Cystic Fibrosis Centre, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne NE1 4LP, UK

Key content:

• Cystic fibrosis is the most common inherited life-threatening disease.
  
• Advances in treatment have led to increased life expectancy.
  
• Increasing numbers of women with cystic fibrosis are choosing to embark on pregnancy; for most, it does not appear to have a detrimental effect on long-term health.
  
• Pregnancy outcomes are generally good but 20% of women do not live to see their child’s tenth birthday.
  

Learning objectives:

• To be aware of the effects of cystic fibrosis on pregnancy.
  
• To understand the importance of preconceptual counselling.
  
• To appreciate that pregnancy management requires a multidisciplinary approach.
  

Ethical issues:

• Should doctors advise women with cystic fibrosis and poor lung function against undertaking pregnancy?
  
• Should assisted reproductive technology be available for women with life-limiting diseases?
  

Please cite this article as: Goddard J, Bourke SJ. Cystic fibrosis and pregnancy. The Obstetrician & Gynaecologist 2009;11:19–24.

Keywords breastfeeding / contraception / diabetes / life expectancy / lung function