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ART babies: a time bomb in the making?

Department of Obstetrics and Gynaecology, Queen's University, Grosvenor Road, Belfast BT12 6BJ, UK. email: i.cooke{at}qub.ac.uk

One in six couples experience difficulties in conceiving. Assisted reproductive technologies (ART) have dramatically improved the clinical and personal outcome for many of these couples. However, it is only now, after these technologies have been in use in clinical practice for a quarter of a century, that the medium- to long-term safety of these interventions is being called into question. Studies comparing the wellbeing of children conceived using ART have been relatively small, resulting in a wide discrepancy in outcomes. There is a view that the Human Fertilisation and Embryology Authority should seek to change the law regarding confidentiality to allow the short- and long-term health of these children to be monitored. This article reviews the current research on perinatal and early childhood outcomes for children conceived using ART.

Keywords Keywords / artificial reproductive technologies / in vitro fertilisation / intracytoplasmic sperm injection / perinatal risks