The Obstetrician & Gynaecologist 2007;9:1:27-33
doi: 10.1576/toag.9.1.027.27293
Copyright © 2007 by the Royal College of Obstetricians and Gynaecologists.
Management of women with inherited bleeding disorders in pregnancy
Claudia Chi, MBBS, Clinical Research Fellow1 and
Rezan A Kadir, MD FRCS MRCOG, Consultant Obstetrician and Gynaecologist2
1. Department of Obstetrics and Gynaecology, Royal Free Hospital, London NW3 2QG, UK
2. Department of Obstetrics and Gynaecology, Royal Free Hospital, Pond Street, London NW3 2QG, UK Email: rezan.abdul-kadir{at}royalfree.nhs.uk (corresponding author)
Key content:
- Pregnancy in women with inherited bleeding disorders requires specialised and individualised care using a multidisciplinary approach with obstetricians, midwives, haematologists and anaesthetists.
- Childbirth presents an intrinsic haemostatic challenge in these women and obstetricians may be the first to encounter haemorrhagic complications.
- An understanding and awareness of these disorders and close collaboration between obstetricians and haematologists are essential in ensuring a successful outcome.
Learning objectives:
- To understand the basic principles in the obstetric management of women with inherited bleeding disorders.
- To know the options available for prenatal diagnosis.
- To be aware of the increased risk of haemorrhagic complications in these women and their offspring.
Ethical issues:
- Advances in prenatal diagnosis and treatment of inherited bleeding disorders create complex dilemmas for families affected by these disorders.
Please cite this article as: Chi C, Kadir RA. Management of women with inherited bleeding disorders in pregnancy. The Obstetrician & Gynaecologist 2007;9:2733.
Keywords carriers of haemophilia / factor XI deficiency / preconceptual counselling / prenatal diagnosis / von Willebrand disease
Copyright © 2007 by the Royal College of Obstetricians and Gynaecologists.