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Handbook of Endometrial Pathology

Written by two pathologists, this book is primarily aimed at trainee and practising histopathologists. The authors believe that it will also be useful to gynaecologists.

It covers the histological features of the endometrium in normal and abnormal circumstances in a clear, readable manner, with comprehensive references and excellent photographs. Although it has the title of ‘handbook’, it is still a comprehensive account and includes descriptions of rare conditions, such as ‘malakoplakia’ and ‘xanthogranulomatous endometritis’, of which few of us will have heard, let alone encountered clinically.

There is an excellent chapter on iatrogenic disease, describing the effects on the endometrium of the combined contraceptive pill, progestogens, tamoxifen, intrauterine contraceptive devices, Mirena® intrauterine system and endometrial ablation. Classification of endometrial hyperplasias is clearly explained and a simple approach based on the presence or absence of atypia defended and promoted. The reasons for abandoning the terms ‘adenocarcinoma in situ’ and ‘endometrial carcinoma in situ’ are explained well.

Of most value, however, is the chapter on endometrial malignancy, in which a full description of the various histological subtypes is given. The clinical significance of serous adenocarcinoma and the presence of clear cells or small cells, all of which are associated with aggression and a poor prognosis, is explained.

The book deals largely with histological descriptions and the lack of clinical discussion limits its worth to general gynaecologists. The chapters on endometrial malignancy and trophoblastic disease, however, are reason enough for trainee and practising gynaecological oncologists to own a copy. For most gynaecologists, however, it will serve as a useful reference book for the library.

Kenney Nicholas, MRCOG, Consultant Obstetrician and Gynaecologist¹

^1. St Mary's Hospital, Isle of Wight, UK

Taylor & Francis/Informa Healthcare, 2005
ISBN 9781841843674
Hardback, 324 pages, £85.00

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