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The Obstetrician & Gynaecologist 2007;9:4:289
doi: 10.1576/toag.9.4.289.27370
Copyright © 2007 by the Royal College of Obstetricians and Gynaecologists.
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Book reviews

Atlas of Preimplantation Genetic Diagnosis: An Illustrated Textbook and Reference for Clinicians

2nd edition

Authors Yury Verlinsky, Anver Kuliev


Figure 1

This beautifully illustrated book is divided into two sections. The first has seven splendid chapters on investigative methods, which are well illustrated and plainly described. Chapter one sets the background science, which can be simply digested by an average gynaecologist, while chapters two to seven are more technical. Techniques of polar body and blastomere biopsies are explained in stages. Step-by-step explanation and discussion of preimplantation genetic diagnosis (PGD) follow for aneuploidies, translocations and single gene disorders. The two remaining chapters discuss nuclear transfer techniques and the future of PGD.

The images and illustrations are all grouped together in the second section of the book, which I like in an atlas. This allows the text to flow easily in the manuscript chapters. The quality of the pictures, flow charts and illustrations in the second section clearly demonstrates the high level of care and professionalism taken in producing and publishing this collection. It also shows in the clear way in which the schematic diagram of a gene defect is combined with its restriction map and the electrophoresis analysis of the concerned mutant and in the illustrations combining family pedigree with the outcome of PGD. The numerous fluorescence in situ hybridisation (FISH) pictures are coherent in their organisation and clearly explained. The clarity of explanation is a prominent feature in almost all of the figures.

I enthusiastically recommend this book to students, our future embryologists and fertility specialists. I also recommend it as a reference book for the library of any laboratory where PGD is performed or where there are plans to develop the PGD service. This book is not for the average gynaecologist but it is certainly for the gynaecologist with an interest in assisted reproduction.

One slight disappointment I had when I picked up the book and noticed its superb illustrations was the absence of a CD-ROM. I wanted to have some of these images on my computer so that I could, with permission, use them in my lectures and presentations.

Adnan Bunkheila, MRCOG, Consultant Obstetrician and Gynaecologist1

1. Singleton Hospital, Swansea, UK

Informa Healthcare/Taylor & Francis, 2005
ISBN 9781842142455
Hardback, 288 pages, £175.00





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